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Symbol Name ID |
Klf4
Kruppel-like transcription factor 4 (gut) MGI:1342287 |
| Darker colors indicate more annotations |
| Human Phenotypes | Hepatocellular carcinoma |
| Disease(s) Associated with KLF4 | |
| hepatocellular carcinoma |
| Mouse Phenotypes | abnormal intestinal goblet cell morphology |
abnormal colon goblet cell morphology |
abnormal tongue epithelium morphology |
abnormal tongue squamous epithelium morphology |
abnormal esophageal epithelium morphology |
abnormal intestinal epithelium morphology |
increased Paneth cell number |
ectopic Paneth cells |
abnormal stomach mucosa morphology |
abnormal gastric gland morphology |
abnormal gastric chief cell morphology |
abnormal gastric parietal cell morphology |
abnormal mucous neck cell morphology |
abnormal gastric surface mucous cell morphology |
abnormal stomach epithelium morphology |
gastric hypertrophy |
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| Availability | Mouse Genotype | ||||||||||||||||
| Klf4tm1.1Khk/Klf4tm1.1Khk | |||||||||||||||||
| Klf4tm1Efu/Klf4tm1Efu | |||||||||||||||||
| Klf4tm1Khk/Klf4tm1Khk Tg(Foxa3-cre)1Khk/0 (conditional) |
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| Klf4tm1Khk/Klf4tm1Khk Tg(ED-L2-cre)267Jkat/0 (conditional) |
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| Klf4tm1Khk/Klf4tm1Khk Tg(Klf4-cre/ERT)1Wai/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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